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Article

Genetic and epigenetic factors affecting carotid intima-media thickness in monozygotic twins.

Gene - 5 Feb 2025

Mori Saho, Arakawa Yuya, Hasegawa Mika, Kato Shiho, Hashimoto Hinako, Yoshioka Saki, Ueda Hiromichi, Research Group Osaka Twin, Watanabe Mikio

Abstract excerpt

BACKGROUND AND AIMS: The intima-media thickness (IMT) of the carotid artery, an indicator of subclinical atherosclerosis, varies in close association with various factors such as diabetes and immune response. The extent of changes in IMT varies among individuals owing to both genetic and epigenetic factors. In this study, we aimed to identify single nucleotide polymorphisms (SNPs) and DNA methylation patterns...

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Identifiers

PMID: 39547361
DOI: 10.1016/j.gene.2024.149093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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