Article
Polymorphisms in pro- and anti-inflammatory cytokine genes and susceptibility to atherosclerosis: a pathological study of 1503 consecutive autopsy cases.
Human molecular genetics - 15 Mar 2007
Oda Kanae, Tanaka Noriko, Arai Tomio, Araki Jungo, Song Yixuan, Zhang Ling, Kuchiba Aya, Hosoi Takayuki, Shirasawa Takuji, Muramatsu Masaaki, Sawabe Motoji
Abstract excerpt
Atherosclerosis is a chronic inflammatory disease in the intima of the arterial wall, where cytokines play a crucial role in the pathogenesis of this disease. However, the question of whether or not genetic variations in the cytokine genes could influence the development of atherosclerosis has be...
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