Article
Associations of Common Genetic Variants on IL-17 Genes and Carotid Intima-Media Thickness.
Journal of atherosclerosis and thrombosis - 1 Nov 2018
Wu Tzu-Wei, Chou Chao-Liang, Chen Yi-Cheng, Juang Yue-Li, Wang Li-Yu
Abstract excerpt
AIM: Atherosclerosis is a chronic inflammatory process of the arterial wall and carotid intima-media thickness (cIMT) is regarded as its early marker. Several members of the IL-17 family are involved in pro-inflammatory functions. The specific aim of the study was to explore the relationships of common genetic variants on IL-17 genes with cIMT thickening. METHODS: In the discovery stage, 146 SNPs on 11 IL-17...
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