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Article

The IL-10 promoter haplotype and cancer risk: evidence from a meta-analysis.

Familial cancer - 1 Sept 2012

Zhang Kui, Zhang Lushun, Wang Xianmin, Zhang Lin

Abstract excerpt

Interleukin-10 (IL-10) plays a key role in immunosuppressive and anti-angiogenic process, suggesting its possible involvement in carcinogenesis. A haplotype formed by polymorphisms at positions -1082 G/A (rs1800896), -819 T/C (rs1800871), and -592 A/C (rs1800872) from the transcriptional start site in the promoter region of the IL-10 gene is a strong determinant for IL-10 production. We systematically reviewed...

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Identifiers

PMID: 22644143
DOI: 10.1007/s10689-012-9533-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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