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Article

Interleukin-10 promoter polymorphism is associated with decreased breast cancer risk.

Breast cancer research and treatment - 1 Mar 2005

Langsenlehner Uwe, Krippl Peter, Renner Wilfried, Yazdani-Biuki Babak, Eder Tanja, Köppel Herwig, Wascher Thomas C, Paulweber Bernhard, Samonigg Hellmut

Abstract excerpt

Interleukin-10 (IL-10) is an immunosuppressive cytokine which may facilitate development of cancer by supporting tumor escape from the immune response. A [TCATA] haplotype formed by polymorphisms at positions -3575, -2763, -1082, -819 and -592 in the promoter of the IL-10 gene is a strong determinant for IL-10 expression. The presence of this haplotype can be determined by analysis of the -592C > A polymorphism....

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PMID: 15803357
DOI: 10.1007/s10549-004-3607-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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