Article
Inflammatory breast cancer: High incidence of GCC haplotypes (-1082A/G, -819T/C, and -592A/C) in the interleukin-10 gene promoter correlates with over-expression of interleukin-10 in patients' carcinoma tissues.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2017
Sabet Salwa, El-Sayed Shrouk Khalaf, Mohamed Hossam Taha, El-Shinawi Mohamed, Mohamed Mona M
Abstract excerpt
Interleukin-10 is involved in carcinogenesis by supporting tumor escape from the immune response. The aim of this study was to assess the single nucleotide polymorphisms, -1082A/G, -819T/C and -592A/C, in interleukin-10 gene promoter in inflammatory breast cancer compared to non-inflammatory breast cancer and association of these polymorphisms with interleukin-10 gene expression. We enrolled 105 breast cancer...
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