Article
The interleukin-10-1082 promoter polymorphism and cancer risk: a meta-analysis.
Mutagenesis - 1 May 2012
Wang Jing, Ding Qi, Shi Ying, Cao Qiang, Qin Chao, Zhu Jian, Chen Jiawei, Yin Changjun
Abstract excerpt
Interleukin-10 (IL-10) is a multifunctional cytokine with both immunosuppressive and anti-angiogenic properties and play an important role in the pathogenesis of cancer. IL-10-1082A>G polymorphism is the most extensively studied polymorphism in the IL-10 gene in cancer susceptibility. To date, a number of case-control studies were conducted to investigate the association between IL-10-1082A>G polymorphism and...
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