Article
Drosophila Dachsous and Fat polarize actin-based protrusions over a restricted domain of the embryonic denticle field.
Developmental biology - 15 Nov 2013
Lawlor Kynan T, Ly Daniel C, DiNardo Stephen
Abstract excerpt
Atypical cadherins Dachsous (Ds) and Fat coordinate the establishment of planar polarity, essential for the patterning of complex tissues and organs. The precise mechanisms by which this system acts, particularly in cases where Ds and Fat act independently of the 'core' frizzled system, are still the subject of investigation. Examining the deployment of the Ds-Fat system in different tissues of the model organism...
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