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Article

HLA and RA revisited: citrullinated food for the SE hypothesis, the DR6 effect, and NIMA.

Human immunology - 1 Jun 2006

de Vries René R P, Huizinga Tom W J, Toes René E M

Abstract excerpt

An obvious way to unravel the apparently complex association between human leukocyte antigen (HLA) and rheumatoid arthritis (RA) is to reduce the heterogeneity of this multifactorial disease. Recently we have discovered that shared epitope (SE)-positive HLA-DRB1 alleles are exclusively associated with a subgroup of RA patients that test positive for auto-antibodies against cyclic citrullinated peptides. Further...

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Share to Arthritis, Rheumatoid
Share to Autoantibodies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16728269
DOI: 10.1016/j.humimm.2006.03.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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