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Article

An independent role of protective HLA class II alleles in rheumatoid arthritis severity and susceptibility.

Arthritis and rheumatism - 1 Sept 2005

van der Helm-van Mil Annette H M, Huizinga Tom W J, Schreuder Geziena M Th, Breedveld Ferdinand C, de Vries René R P, Toes René E M

Abstract excerpt

OBJECTIVE: To prospectively investigate the effect of the DERAA-encoding HLA alleles on disease susceptibility and severity in a large cohort of patients with rheumatoid arthritis (RA), and to differentiate protective effects from non-predisposition by comparing subgroups of patients with an equal amount of predisposition alleles. METHODS: HLA class II alleles were determined in 440 patients with early RA and in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16142711
DOI: 10.1002/art.21272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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