Article
The mec-4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degeneration.
Nature - 14 Feb 1991
Driscoll M, Chalfie M
Abstract excerpt
Three dominant mutations of mec-4, a gene needed for mechanosensation, cause the touch-receptor neurons of Caenorhabditis elegans to degenerate. With deg-1, another C. elegans gene that can mutate to induce neuronal degeneration and that is similar in sequence, mec-4 defines a new gene family. Cr...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Caenorhabditis
- Chromosome Mapping
- Cloning, Molecular
- Genes
- Genetic Complementation Test
- Mechanoreceptors
- Molecular Sequence Data
- Multigene Family
- Mutation