Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A stomatin-like protein necessary for mechanosensation in C. elegans.

Nature - 16 Nov 1995

Huang M, Gu G, Ferguson E L, Chalfie M

Abstract excerpt

The mec-2 gene is required for the function of a set of six touch receptor neurons in the nematode Caenorhabditis elegans; mec-2 mutants, which are touch-insensitive, have touch cells that appear morphologically normal. Gene interaction studies suggest that mec-2 positively regulates the activity of the putative mechanosensory transduction channel (and the present paper), comprised in part of proteins encoded by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Cloning, Molecular
Share to Exons

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Membrane Proteins

Share to Molecular Sequence Data

Share to Mutation

Share to Recombinant Fusion Proteins

Share to Restriction Mapping

Source

Identifiers

PMID: 7477350
DOI: 10.1038/378292a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A stomatin-like protein necessary for mechanosensation in C. elegans.PMID 7477350Read ↗

MEC-2 is recruited to the putative mechanosensory complex in C. elegans touch receptor neurons through its stomatin-like domain.Semantic proximity Read ↗

MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation.Semantic proximity Read ↗

The mec-2e isoform with a large C-terminal completely rescues the touch sensation defect of C. elegansSemantic proximity Read ↗

Spatial asymmetry in the mechanosensory phenotypes of the C. elegans DEG/ENaC gene mec-10.Semantic proximity Read ↗

A stomatin-domain protein essential for touch sensation in the mouse.Semantic proximity Read ↗

Molecules that mediate touch transduction in the nematode Caenorhabditis elegans.Semantic proximity Read ↗

Caenorhabditis elegans paraoxonase-like proteins control the functional expression of DEG/ENaC mechanosensory proteins.Semantic proximity Read ↗

Extracellular proteins organize the mechanosensory channel complex in C. elegans touch receptor neurons.Semantic proximity Read ↗

MEC-10 and MEC-19 Reduce the Neurotoxicity of the MEC-4(d) DEG/ENaC Channel in Caenorhabditis elegans.Semantic proximity Read ↗

MEC-12, an α-tubulin required for touch sensitivity in C. elegansSemantic proximity Read ↗

A transmembrane domain of the putative channel subunit MEC-4 influences mechanotransduction and neurodegeneration in C. elegans.Semantic proximity Read ↗

Regulation of Caenorhabditis elegans degenerin proteins by a putative extracellular domain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.