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Article

MEC-2 is recruited to the putative mechanosensory complex in C. elegans touch receptor neurons through its stomatin-like domain.

Current biology : CB - 9 Nov 2004

Zhang Shifang, Arnadottir Johanna, Keller Charles, Caldwell Guy A, Yao C Andrea, Chalfie Martin

Abstract excerpt

BACKGROUND: The response to gentle body touch in C. elegans requires a degenerin channel complex containing four proteins (MEC-2, MEC-4, MEC-6, and MEC-10). The central portion of the integral membrane protein MEC-2 contains a stomatin-like region that is highly conserved from bacteria to mammals. The molecular function of this domain in MEC-2, however, is unknown. RESULTS: Here, we show that MEC-2 colocalizes...

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Identifiers

PMID: 15530389
DOI: 10.1016/j.cub.2004.10.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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