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Article

Genetic mapping of new DNA probes at Xq27 defines a strategy for DNA studies in the fragile X syndrome.

American journal of human genetics - 1 Mar 1991

Suthers G K, Mulley J C, Voelckel M A, Dahl N, Väisänen M L, Steinbach P, Glass I A, Schwartz C E, van Oost B A, Thibodeau S N

Abstract excerpt

The fragile X syndrome is the most common cause of familial mental retardation and is characterized by a fragile site at the end of the long arm of the X chromosome. The unusual genetics and cytogenetics of this X-linked condition make genetic counseling difficult. DNA studies were of limited value in genetic counseling, because the nearest polymorphic DNA loci had recombination fractions of 12% or more with the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 1671806
PMCID: PMC1682966

Genes

IDS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic mapping of new DNA probes at Xq27 defines a strategy for DNA studies in the fragile X syndrome.PMID 1671806Read ↗

Genetic mapping of two new DNA markers in Xq26-q28 relative to the fragile-X syndrome locus.Semantic proximity Read ↗

Physical mapping of new DNA probes near the fragile X mutation (FRAXA) by using a panel of cell lines.Semantic proximity Read ↗

DNA linkage analysis of 26 families with fragile X syndrome.Semantic proximity Read ↗

Isolation of sequences that span the fragile X and identification of a fragile X-related CpG island.Semantic proximity Read ↗

Fragile X syndrome: diagnosis using highly polymorphic microsatellite markers.Semantic proximity Read ↗

Linear order of new and established DNA markers around the fragile site at Xq27.3.Semantic proximity Read ↗

DNA studies of X-linked mental retardation associated with a fragile site at Xq27.Semantic proximity Read ↗

Molecular characterization of a DNA probe, U6.2, located close to the fragile X locus.Semantic proximity Read ↗

Molecular analysis of the fragile X syndrome.Semantic proximity Read ↗

A linkage map of microsatellite markers on the human X chromosome.Semantic proximity Read ↗

Isolation and characterization of a highly polymorphic human locus (DXS455) in proximal Xq28.Semantic proximity Read ↗

Isolation and characterization of three microsatellite markers in the proximal long arm of the human X chromosome.Semantic proximity Read ↗

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