Article
Physical mapping of new DNA probes near the fragile X mutation (FRAXA) by using a panel of cell lines.
American journal of human genetics - 1 Aug 1990
Suthers G K, Hyland V J, Callen D F, Oberle I, Rocchi M, Thomas N S, Morris C P, Schwartz C E, Schmidt M, Ropers H H
Abstract excerpt
The fragile X syndrome is a very common disorder, but there has been little progress toward isolating the fragile X mutation (FRAXA). We describe a panel of 14 somatic cell hybrid lines, lymphoblastoid cell lines, and peripheral lymphocytes with X-chromosome translocation or deletion breakpoints...
Topics
- Animals
- Cell Line
- Chromosome Banding
- Cricetinae
- DNA Probes
- Female
- Fragile X Syndrome
- Genetic Markers
- Humans
- Hybrid Cells
- Male
- Mice
- Mutation
- Restriction Mapping
- Sex Chromosome Aberrations
- X Chromosome