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Article

Physical mapping of new DNA probes near the fragile X mutation (FRAXA) by using a panel of cell lines.

American journal of human genetics - 1 Aug 1990

Suthers G K, Hyland V J, Callen D F, Oberle I, Rocchi M, Thomas N S, Morris C P, Schwartz C E, Schmidt M, Ropers H H

Abstract excerpt

The fragile X syndrome is a very common disorder, but there has been little progress toward isolating the fragile X mutation (FRAXA). We describe a panel of 14 somatic cell hybrid lines, lymphoblastoid cell lines, and peripheral lymphocytes with X-chromosome translocation or deletion breakpoints near FRAXA. The locations of the breakpoints were defined with 16 established probes between pX45d (DXS100) and St14-1...

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PMID: 2378346
PMCID: PMC1683725

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