Genetic mapping of two new DNA markers in Xq26-q28 relative to the fragile-X syndrome locus.

Article

Genetic mapping of two new DNA markers in Xq26-q28 relative to the fragile-X syndrome locus.

American journal of human genetics - 1 Sept 1990

Sood R, Mulligan L M, Poon R, White B N, Holden J J

Abstract excerpt

We have characterized and genetically mapped two new DNA markers (DXS311 and DXS312) with respect to 10 existing loci in Xq26----Xq28 in a set of 15 families in which the fragile-X [fra(X)] syndrome was segregating. Two-point and multipoint linkage analyses were performed taking into account the...

Topics

Chromosome Mapping
DNA Probes
Fragile X Syndrome
Genetic Linkage
Genetic Markers
Humans
Mutation
Polymorphism, Restriction Fragment Length
Sex Chromosome Aberrations
X Chromosome

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