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Article

Linear order of new and established DNA markers around the fragile site at Xq27.3.

Genomics - 1 May 1991

Hirst M C, Roche A, Flint T J, MacKinnon R N, Bassett J H, Nakahori Y, Watson J E, Bell M V, Patterson M N, Boyd Y

Abstract excerpt

We have used recombinant clones derived from microdissection of the fragile X region to characterize breakpoints around the fragile site at Xq27.3. So far, no microdissection markers derived from Xq28 material have been found, thus allowing a rapid screening for clones surrounding the fragile site by their presence in a somatic cell hybrid containing Xq27.2-Xqter. A total of 43 new DNA markers from Xq27 have been...

Topics

Blotting, Southern
Cell Line
Cloning, Molecular
Fragile X Syndrome
Genetic Markers
Humans
Mutation
Polymerase Chain Reaction
X Chromosome

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2045104
DOI: 10.1016/0888-7543(91)90506-a

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2045104-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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