Article
Molecular analysis of the fragile X syndrome.
Journal of inherited metabolic disease - 1 Jan 1992
Hirst M C, Knight S M, Nakahori Y, Roche A, Davies K E
Abstract excerpt
The molecular analysis of human X-linked disease has progressed rapidly over the last few years owing to advances in power of mapping techniques. Physical DNA maps covering more than 5 million base pairs have been constructed for several chromosomal regions. Many of these regions have now also been cloned into overlapping cosmid and YAC contigs facilitating the search for disease genes. The recent identification...
Topics
- Chromosome Mapping
- Chromosomes, Fungal
- Fragile X Syndrome
- Gene Library
- Genome, Human
- Humans
- Male
- Methylation
- Mutation