DNA studies of X-linked mental retardation associated with a fragile site at Xq27.

doi:10.1002/ajmg.1320230157

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Article

DNA studies of X-linked mental retardation associated with a fragile site at Xq27.

American journal of medical genetics - 1 Jan 2000

Davies K E

Abstract excerpt

X-linked mental retardation associated with expression of a fragile site at Xq27.3 has attracted much interest because transmission can occur through phenotypically normal males. Several theories have been proposed to explain the segregation pattern. Linkage analysis in affected families indicates a high frequency of recombination around this site in some families, although in others the genetic relationships are...

Topics

Animals
Chromosome Fragile Sites
Chromosome Fragility
Cloning, Molecular
Cosmids
Cricetinae
DNA
Female
Fragile X Syndrome
Genetic Linkage
Genetic Markers
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hybrid Cells

Intellectual Disability

Male

Mutation

Sex Chromosome Aberrations

X Chromosome

Source

Open in PubMed

Identifiers

PMID: 3513572
DOI: 10.1002/ajmg.1320230157

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3513572-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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