Isolation and characterization of a highly polymorphic human locus (DXS455) in proximal Xq28.

doi:10.1016/0888-7543(92)90299-8

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Article

Isolation and characterization of a highly polymorphic human locus (DXS455) in proximal Xq28.

Genomics - 1 Apr 1992

Consalez G G, Stayton C L, Freimer N B, Goonewardena P, Brown W T, Gilliam T C, Warren S T

Abstract excerpt

Human Xq28 is highly gene dense with over 27 loci. Because most of these genes have been mapped by linkage to polymorphic loci, only one of which (DXS52) is informative in most families, a search was conducted for new, highly polymorphic Xq28 markers. From a cosmid library constructed using a som...

Topics

Alleles
Chromosome Mapping
Cosmids
Female
Fragile X Syndrome
Genetic Markers
Heterozygote
Humans
Male
Pedigree
Polymorphism, Genetic
X Chromosome

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