Article
Isolation and characterization of a highly polymorphic human locus (DXS455) in proximal Xq28.
Genomics - 1 Apr 1992
Consalez G G, Stayton C L, Freimer N B, Goonewardena P, Brown W T, Gilliam T C, Warren S T
Abstract excerpt
Human Xq28 is highly gene dense with over 27 loci. Because most of these genes have been mapped by linkage to polymorphic loci, only one of which (DXS52) is informative in most families, a search was conducted for new, highly polymorphic Xq28 markers. From a cosmid library constructed using a somatic cell hybrid containing human Xq27.3----qter as the sole human DNA, a human-insert cosmid (c346) was identified and...
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