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Article

Modulation of telomere terminal structure by telomerase components in Candida albicans.

Nucleic acids research - 1 Jan 2006

Steinberg-Neifach Olga, Lue Neal F

Abstract excerpt

The telomerase ribonucleoprotein in Candida albicans is presumed to contain at least three Est proteins: CaEst1p, CaEst2p/TERT and CaEst3p. We constructed mutants missing each of the protein subunit of telomerase and analyzed overall telomere dynamics and single-stranded telomere overhangs over the course of many generations. The est1-DeltaDelta mutant manifested abrupt telomere loss and recovery, consistent with...

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Identifiers

PMID: 16714448
DOI: 10.1093/nar/gkl345
PMCID: PMC1464115

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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