Article
Large telomerase RNA, telomere length heterogeneity and escape from senescence in Candida glabrata.
FEBS letters - 19 Nov 2009
Kachouri-Lafond R, Dujon B, Gilson E, Westhof E, Fairhead C, Teixeira M T
Abstract excerpt
Telomerase, the key enzyme essential for the maintenance of eukaryotic chromosome ends, contains a reverse transcriptase and an RNA that provides the template for the synthesis of telomeric repeats. Here, we characterize the telomerase subunits in the hemiascomycete yeast Candida glabrata. We propose a secondary structure model for the telomerase RNA that is the largest described to date. Telomerase deletion...
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