Article
Genome-wide association: a promising start to a long race.
Trends in genetics : TIG - 1 Jul 2006
Evans David M, Cardon Lon R
Abstract excerpt
A recent study by Cheung et al. demonstrates how to identify expression quantitative trait loci (eQTLs) underlying gene expression phenotypes through a combination of genome-wide linkage analysis and subsequent fine mapping or by genome-wide association (GWA) analysis. This study emphasizes the complexity of human traits, highlighting the challenges faced by investigators--in particular, insufficient linkage...
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