Article
Revealing the architecture of gene regulation: the promise of eQTL studies.
Trends in genetics : TIG - 1 Aug 2008
Gilad Yoav, Rifkin Scott A, Pritchard Jonathan K
Abstract excerpt
Expression quantitative trait loci (eQTL) mapping studies have become a widely used tool for identifying genetic variants that affect gene regulation. In these studies, expression levels are viewed as quantitative traits, and gene expression phenotypes are mapped to particular genomic loci by combining studies of variation in gene expression patterns with genome-wide genotyping. Results from recent eQTL mapping...
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