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Article

Mapping complex disease traits with global gene expression.

Nature reviews. Genetics - 1 Mar 2009

Cookson William, Liang Liming, Abecasis Gonçalo, Moffatt Miriam, Lathrop Mark

Abstract excerpt

Variation in gene expression is an important mechanism underlying susceptibility to complex disease. The simultaneous genome-wide assay of gene expression and genetic variation allows the mapping of the genetic factors that underpin individual differences in quantitative levels of expression (expression QTLs; eQTLs). The availability of systematically generated eQTL information could provide immediate insight...

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PMID: 19223927
DOI: 10.1038/nrg2537
PMCID: PMC4550035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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