Article
Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS.
PLoS genetics - 1 Apr 2010
Nicolae Dan L, Gamazon Eric, Zhang Wei, Duan Shiwei, Dolan M Eileen, Cox Nancy J
Abstract excerpt
Although genome-wide association studies (GWAS) of complex traits have yielded more reproducible associations than had been discovered using any other approach, the loci characterized to date do not account for much of the heritability to such traits and, in general, have not led to improved understanding of the biology underlying complex phenotypes. Using a web site we developed to serve results of expression...
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