Article
Genetic Regulation of Cortical and Trabecular Bone Strength and Microstructure in Inbred Strains of Mice
1 Jun 2000
Abstract excerpt
The inbred strains of mice C57BL/6J (B6) and C3H/HeJ (C3H) have very different femoral peak bone densities and may serve as models for studying the genetic regulation of bone mass. Our objective was to further define the bone biomechanics and microstructure of these two inbred strains. Microarchitecture of the proximal femur, femoral midshaft, and lumbar vertebrae were evaluated in three dimensions using...
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