Article
Mapping quantitative trait loci that influence femoral cross-sectional area in mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Oct 2002
Klein Robert F, Turner Renn J, Skinner Lisa D, Vartanian Kristina A, Serang Maqsood, Carlos Amy S, Shea Marie, Belknap John K, Orwoll Eric S
Abstract excerpt
Size and shape are critical determinants of the mechanical properties of skeletal elements and can be anticipated to be highly heritable. Moreover, the genes responsible may be independent of those that regulate bone mineral density (BMD). To begin to identify the heritable determinants of skeletal geometry, we have examined femoral cross-sectional area (FCSA) in male and female mice from two inbred strains of...
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