Article
CTLA4 gene polymorphisms and soluble CTLA4 protein in Behcet's disease.
Tissue antigens - 1 Sept 2009
Park K S, Baek J A, Do J E, Bang D, Lee E-S
Abstract excerpt
Cytotoxic T lymphocyte antigen 4 (CTLA4; CD152) is a costimulatory molecule expressed on activated T cells that plays a key inhibitory role during T lymphocyte activation. The gene encoding for CTLA4 has been suggested as a candidate for conferring susceptibility to autoinflammatory diseases. We investigated the polymorphisms of the CTLA4 gene [promoter region (-1722 T/C, -1661 A/G and -318 C/T) and exon 1 (+49...
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