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Article

Polymorphism analysis of the CTLA-4 gene in paracoccidioidomycosis patients.

Memorias do Instituto Oswaldo Cruz - 1 Mar 2011

Lozano Viviane F, Lins Tulio C, Teixeira Marcus M, Vieira Rodrigo G, Blotta Maria Heloisa Sl, Goes Alfredo M, Silva Izabel Cristina R, Pereira Rinaldo W, Bocca Anamelia L, Felipe Maria Sueli S

Abstract excerpt

The CTLA-4 protein is expressed in activated T cells and plays an essential role in the immune response through its regulatory effect on T cell activation. Polymorphisms of the CTLA-4 gene have been correlated with autoimmune, neoplastic and infectious illnesses. This work aimed to verify possible associations between single nucleotide polymorphisms (SNPs) in CTLA-4, -318C/T in the promoter and +49A/G in exon 1...

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Identifiers

PMID: 21537684
DOI: 10.1590/s0074-02762011000200017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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