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Article

Pleiotropic-resistant phenotype is a multifactorial phenomenon in human colon carcinoma cell lines.

British journal of cancer - 1 Jan 1991

Toffoli G, Viel A, Tumiotto L, Biscontin G, Rossi C, Boiocchi M

Abstract excerpt

The biochemical basis of multidrug-resistant (MDR) phenotype has been investigated in drug-resistant sublines independently obtained in our laboratories by single step doxorubicin (DOX) selection of LoVo, DLD1, and SW948 human colon carcinoma (HCC) cell lines. All the chemoresistant sublines have been found to be cross-resistant to DOX, actinomycin-D (ACT-D) and vincristine (VCR) but not to...

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Identifiers

PMID: 1671208
DOI: 10.1038/bjc.1991.11
PMCID: PMC1971628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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