[Resistance to chemotherapeutic agents in the treatment of cancer. Emphasizing the multiresistant phenotype].

Abstract excerpt

Despite considerable efforts, rather limited progress has been achieved in the treatment of disseminated cancer with chemotherapeutic agents during the last decade. Most tumours, especially those of epithelial origin, are more or less resistant to cytostatics right from initiation of therapy. Other tumours, on the other hand, like leukemias and lymphomas, are highly responsive initially but may become resistant...

Topics

• Antineoplastic Agents
• Cell Membrane
• Drug Resistance
• Humans
• Neoplasms
• Phenotype