Biological characterization of multidrug-resistant human colon carcinoma sublines induced/selected by two methods.

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Article

Biological characterization of multidrug-resistant human colon carcinoma sublines induced/selected by two methods.

Cancer research - 1 Jun 1990

Yang L Y, Trujillo J M

Abstract excerpt

Two independent multidrug-resistant (MDR) sublines, AdR1.2 and SRA1.2, were developed from the established human colon carcinoma cell line LoVo. AdR1.2 was developed by a long-term continuous exposure of LoVo cells to Adriamycin in stepwise increments of concentration; SRA1.2 was selected/induced...

Topics

Adenocarcinoma
Antineoplastic Agents
Cell Division
Colonic Neoplasms
Doxorubicin
Drug Resistance
Electrophoresis, Polyacrylamide Gel
Gene Amplification
Humans
Membrane Proteins
Molecular Weight
Neoplasm Proteins
Phenotype
Phosphorylation
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 2334917

Genes

SRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2334917-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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