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Article

Prediction of Broad Spectrum Resistance of Tumors towards Anticancer Drugs

15 Apr 2008

Abstract excerpt

PURPOSE: Drug resistance is a major obstacle in cancer chemotherapy. Although the statistical probability of therapeutic success is known for larger patient groups from clinical therapy trials, it is difficult to predict the individual response of tumors. The concept of individualized therapy aims to determine in vitro the drug response of tumors beforehand to choose effective treatment options for each...

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PMID: 18413831
DOI: 10.1158/1078-0432.ccr-07-4525

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