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Article

Photocarcinogenesis and susceptibility to UV radiation in the v-Ha-ras transgenic Tg.AC mouse.

The Journal of investigative dermatology - 1 Sept 1998

Trempus C S, Mahler J F, Ananthaswamy H N, Loughlin S M, French J E, Tennant R W

Abstract excerpt

The v-Ha-ras transgenic Tg.AC mouse line has proven to be a useful model for the study of chemical carcinogenic potential. We undertook experiments designed to study the effect of the physical carcinogen, UV radiation, on tumorigenesis in this mouse strain. Following a total of three exposures on...

Topics

Animals
Disease Models, Animal
Dose-Response Relationship, Radiation
Female
Genes, p53
Genes, ras
Mice
Mice, Transgenic
Mutation
Neoplasms, Radiation-Induced
Papilloma
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Radiation Tolerance

Ultraviolet Rays

Source

Identifiers

PMID: 9740239
DOI: 10.1046/j.1523-1747.1998.00237.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9740239-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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