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Article

The terminal telomeric DNA sequence determines the mechanism of dysfunctional telomere fusion.

Molecular cell - 30 Jul 2010

Stohr Bradley A, Xu Lifeng, Blackburn Elizabeth H

Abstract excerpt

Mammalian telomeres consist of tandem DNA repeats that bind protective protein factors collectively termed shelterins. Telomere disruption typically results in genome instability induced by telomere fusions. The mechanism of telomere fusion varies depending on the means of telomere disruption. Here, we investigate telomere fusions caused by overexpression of mutant telomerases that add mutated telomeric repeats,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20670897
DOI: 10.1016/j.molcel.2010.06.020
PMCID: PMC2920734

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ATM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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