Article
Comprehensive allelotyping of human intrahepatic cholangiocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2001
Momoi H, Okabe H, Kamikawa T, Satoh S, Ikai I, Yamamoto M, Nakagawara A, Shimahara Y, Yamaoka Y, Fukumoto M
Abstract excerpt
We performed a genome-wide scan for loss of heterozygosity (LOH) in 22 intrahepatic cholangiocarcinoma (ICC) cases using 168 polymorphic microsatellite markers throughout all of the human chromosomes and 48 markers of which LOH is reportedly characteristic of hepatocellular carcinoma (HCC). Markers with LOH in more than 30% of informative cases were observed at 21 loci. Among these, eight markers on 6q (three...
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