Article
Non-chemotactic Dictyostelium discoideum mutants with altered cGMP signal transduction.
The Journal of cell biology - 1 Dec 1993
Kuwayama H, Ishida S, Van Haastert P J
Abstract excerpt
Folic acid and cAMP are chemoattractants in Dictyostelium discoideum, which bind to different surface receptors. The signal is transduced from the receptors via different G proteins into a common pathway which includes guanylyl cyclase and acto-myosin. To investigate this common pathway, ten muta...
Topics
- 3',5'-Cyclic-GMP Phosphodiesterases
- Animals
- Chemotaxis
- Cyclic GMP
- Dictyostelium
- Folic Acid
- GTP-Binding Proteins
- Genes, Fungal
- Genetic Linkage
- Guanylate Cyclase
- Inositol 1,4,5-Trisphosphate
- Mutation
