Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

C. elegans germ cells switch between distinct modes of double-strand break repair during meiotic prophase progression.

PLoS genetics - 1 Nov 2007

Hayashi Michiko, Chin Gregory M, Villeneuve Anne M

Abstract excerpt

Chromosome inheritance during sexual reproduction relies on deliberate induction of double-strand DNA breaks (DSBs) and repair of a subset of these breaks as interhomolog crossovers (COs). Here we provide a direct demonstration, based on our analysis of rad-50 mutants, that the meiotic program in Caenorhabditis elegans involves both acquisition and loss of a specialized mode of double-strand break repair (DSBR)....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Pairing
Share to Crossing Over, Genetic
Share to DNA Breaks, Double-Stranded

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endodeoxyribonucleases

Share to Esterases

Share to Germ Cells

Share to Rad51 Recombinase

Share to Radiation, Ionizing

Source

Open in PubMed Open full text

Identifiers

PMID: 17983271
DOI: 10.1371/journal.pgen.0030191
PMCID: PMC2048528

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

C. elegans germ cells switch between distinct modes of double-strand break repair during meiotic prophase progression.PMID 17983271Read ↗

PARG establishes a functional module with BRCA1-BARD1 that controls DNA repair pathway choice during gametogenesisSemantic proximity Read ↗

Interdependent and separable functions of <i>C. elegans</i> MRN-C complex members couple formation and repair of meiotic DSBsSemantic proximity Read ↗

C. elegans BRC-1-BRD-1 functions at an early step of DSB processing and inhibits supernumerary crossovers during male meiosisSemantic proximity Read ↗

Identification of DSB-1, a protein required for initiation of meiotic recombination in Caenorhabditis elegans, illuminates a crossover assurance checkpoint.Semantic proximity Read ↗

Meiotic Double-Strand Break Proteins Influence Repair Pathway Utilization.Semantic proximity Read ↗

A link between meiotic prophase progression and crossover control.Semantic proximity Read ↗

Aging Negatively Impacts DNA Repair and Bivalent Formation in the C. elegans Germ LineSemantic proximity Read ↗

C. elegans mre-11 is required for meiotic recombination and DNA repair but is dispensable for the meiotic G(2) DNA damage checkpoint.Semantic proximity Read ↗

Loss of Meiotic Double Strand Breaks Triggers Recruitment of Recombination-independent Pro-crossover Factors in <i>C. elegans</i> SpermatogenesisSemantic proximity Read ↗

ZTF-8 interacts with the 9-1-1 complex and is required for DNA damage response and double-strand break repair in the C. elegans germline.Semantic proximity Read ↗

Active maintenance of meiosis-specific chromosome structures in Caenorhabditis elegans by the deubiquitinase DUO-1.Semantic proximity Read ↗

Joint molecule resolution requires the redundant activities of MUS-81 and XPF-1 during Caenorhabditis elegans meiosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.