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Article

Analysis of a germ line polymorphism of the p53 gene in lung cancer patients; discrete results with smoking history.

Carcinogenesis - 1 Feb 1996

Murata M, Tagawa M, Kimura M, Kimura H, Watanabe S, Saisho H

Abstract excerpt

The p53 tumor suppressor gene is often mutated in various human cancers and a common polymorphism is known at codon 72 of exon 4, with two alleles encoding either arginine (CGC) or proline (CCC). Association of this polymorphism with any human cancer susceptibility has yet to be clarified. We have conducted a case-control study in Japan on the distribution of the three genotypes with 191 lung cancer patients, 152...

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PMID: 8625447
DOI: 10.1093/carcin/17.2.261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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