Article
Influence of polymorphism at p53, CYP1A1 and GSTM1 loci on p53 mutation and association of p53 mutation with prognosis in lung cancer.
Zhonghua yi xue za zhi = Chinese medical journal; Free China ed - 1 Jul 1999
Wang Y C, Chen C Y, Wang H J, Chen S K, Chang Y Y, Lin P
Abstract excerpt
BACKGROUND: We previously found that the majority (9/11) of p53 tumor suppressor gene mutations in 60 lung cancer patients in Taiwan were small intragenic deletions and nonsense mutations. To gain insights into the possible etiologic factors involved in these mutations and the prognostic significance of p53 gene mutations in lung cancer in Taiwan, we investigated the influence of polymorphism at p53, cytochrome...
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