Article
Independent roles of Drosophila Moesin in imaginal disc morphogenesis and hedgehog signalling.
Mechanisms of development - 1 May 2006
Molnar Cristina, de Celis Jose F
Abstract excerpt
The three ERM proteins (Ezrin, Radixin and Moesin) form a conserved family required in many developmental processes involving regulation of the cytoskeleton. In general, the molecular function of ERM proteins is to link specific membrane proteins to the actin cytoskeleton. In Drosophila, loss of moesin (moe) activity causes incorrect localisation of maternal determinants during oogenesis, failures in rhabdomere...
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