Article
Rho1 regulates signaling events required for proper Drosophila embryonic development.
Developmental biology - 1 Feb 2005
Magie Craig R, Parkhurst Susan M
Abstract excerpt
The Rho small GTPase has been implicated in many cellular processes, including actin cytoskeletal regulation and transcriptional activation. The molecular mechanisms underlying Rho function in many of these processes are not yet clear. Here we report that in Drosophila, reduction of maternal Rho1 compromises signaling pathways consistent with defects in membrane trafficking events. These mutants fail to maintain...
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