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Article

EGF receptor signalling protects smooth-cuticle cells from apoptosis during Drosophila ventral epidermis development.

Development (Cambridge, England) - 1 Apr 2004

Urban Sinisa, Brown Gemma, Freeman Matthew

Abstract excerpt

Patterning of the Drosophila ventral epidermis is a tractable model for understanding the role of signalling pathways in development. Interplay between Wingless and EGFR signalling determines the segmentally repeated pattern of alternating denticle belts and smooth cuticle: spitz group genes, which encode factors that stimulate EGFR signalling, induce the denticle fate, while Wingless signalling antagonizes the...

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Identifiers

PMID: 15084467
DOI: 10.1242/dev.01058

Genes

EGFR
EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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