Article
Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout.
The Journal of biological chemistry - 22 Jan 1999
Doi Y, Itoh M, Yonemura S, Ishihara S, Takano H, Noda T, Tsukita S
Abstract excerpt
Ezrin/radixin/moesin (ERM) proteins are general cross-linkers between the plasma membrane and actin filaments. Because their expression is regulated in a tissue-specific manner, each ERM protein has been proposed to have unique functions. On the other hand, experiments at the cellular level and i...
Topics
- Actins
- Animals
- Blood Proteins
- Cell Adhesion
- Cell Movement
- Cytoskeletal Proteins
- Cytoskeleton
- Male
- Membrane Proteins
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
