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Article

New cytochrome P450 2D6*56 allele identified by genotype/phenotype analysis of cryopreserved human hepatocytes.

Drug metabolism and disposition: the biological fate of chemicals - 1 Aug 2006

Li Li, Pan Run-Mei, Porter Todd D, Jensen Neil S, Silber Paul, Russo Guy, Tine John A, Heim John, Ring Barbara, Wedlund Peter J

Abstract excerpt

Genotype/phenotype analysis with human hepatocytes has identified a new inactive CYP2D6 allele, CYP2D6*56. Cryopreserved human hepatocytes from 51 livers were evaluated for CYP2D6 activity with dextromethorphan as the probe substrate. Hepatocyte lots that lacked CYP2D6 activity were further evalu...

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Source

Identifiers

PMID: 16679388
DOI: 10.1124/dmd.106.009548

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CGA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16679388-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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