Article
The high-frequency major histocompatibility complex class I allele Mamu-B*17 is associated with control of simian immunodeficiency virus SIVmac239 replication.
Journal of virology - 1 May 2006
Yant Levi J, Friedrich Thomas C, Johnson Randall C, May Gemma E, Maness Nicholas J, Enz Alissa M, Lifson Jeffrey D, O'Connor David H, Carrington Mary, Watkins David I
Abstract excerpt
Particular HLA alleles are associated with reduced human immunodeficiency virus replication. It has been difficult, however, to characterize the immune correlates of viral control. An analysis of the influence of major histocompatibility complex class I alleles on viral control in 181 simian immunodeficiency virus SIVmac239-infected rhesus macaques revealed that Mamu-B(*)17 was associated with a 26-fold reduction...
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