Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses.

doi:10.1128/jvi.77.16.9029-9040.2003

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Article

Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses.

Journal of virology - 1 Aug 2003

O'Connor David H, Mothe Bianca R, Weinfurter Jason T, Fuenger Sarah, Rehrauer William M, Jing Peicheng, Rudersdorf Richard R, Liebl Max E, Krebs Kendall, Vasquez Joshua, Dodds Elizabeth, Loffredo John, Martin Sarah, McDermott Adrian B, Allen Todd M, Wang Chenxi, Doxiadis G G, Montefiori David C, Hughes Austin, Burton Dennis R, Allison David B, Wolinsky Steven M, Bontrop Ronald, Picker Louis J, Watkins David I

Abstract excerpt

Certain major histocompatibility complex class I (MHC-I) alleles are associated with delayed disease progression in individuals infected with human immunodeficiency virus (HIV) and in macaques infected with simian immunodeficiency virus (SIV). However, little is known about the influence of these MHC alleles on acute-phase cellular immune responses. Here we follow 51 animals infected with SIV(mac)239 and...

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PMID: 12885919
DOI: 10.1128/jvi.77.16.9029-9040.2003
PMCID: PMC167227

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Source receipt: pubmed, retrieved 7 Sept 2026.

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