Evidence for a common molecular pathogenesis in colorectal, gastric, and pancreatic cancer.

doi:10.1002/gcc.2870030609

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Article

Evidence for a common molecular pathogenesis in colorectal, gastric, and pancreatic cancer.

Genes, chromosomes & cancer - 1 Nov 1991

Neuman W L, Wasylyshyn M L, Jacoby R, Erroi F, Angriman I, Montag A, Brasitus T, Michelassi F, Westbrook C A

Abstract excerpt

We examined tissue extracted from 19 gastric, 7 pancreatic, and 23 colorectal carcinoma specimens to determine the comparative incidence of allele loss on chromosomes 5, 17, and 18 and that of KRAS2 point mutations. Chromosome 5 allele loss occurred at the same frequency in all three gastrointest...

Topics

Adenocarcinoma
Adenomatous Polyposis Coli
Alleles
Base Sequence
Carcinoma
Chromosome Deletion
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 18
Chromosomes, Human, Pair 5
Colorectal Neoplasms
DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

DNA, Neoplasm

Genetic Predisposition to Disease

Humans

Molecular Sequence Data

Oncogenes

Pancreatic Neoplasms

Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 1663781
DOI: 10.1002/gcc.2870030609

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1663781-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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