Article
Obtaining unbiased estimates of tagging SNP performance.
Annals of human genetics - 1 Mar 2006
Iles M M
Abstract excerpt
The use of tagging SNPs (tSNPs) as a cost-effective means of capturing genetic diversity is widespread. However, the quality of the tSNPs selected is dependent on the initial sample in which they are characterized. If the initial marker set is too sparse the tSNPs chosen will capture less information than a naïve analysis suggests. A simple method has been proposed that should provide a better estimate of the...
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